A group of rappers are wanting to hit it big in the music business. When one of them gets marked by this lady his face starts to burn unbearably. As he follows the path which makes his pain ease he ends up at a strip club called Cryptz. There he finds that his pain in his face has eased, and once inside he finds Cryptz to be all that he thought it would be, plus a little more. Once night falls the doors to Cryptz is locked and everyone is locked inside. Now they discover that this club is more than just a club, it's a home for vampires and they must survive the night and battle the vampires in order to survive. Only Tymez, who is our star has a tattoo that the vampires want. With this tattoo, the vampires are able to rule the planet and end humanity.
The movie opens with a nice, violent and gory killing where a vampire kills this guy; after that we meet Tymez. Tymez is pretty much a lazy guy and his mother is after him on getting a job. He tells her that he is the next Jay-Z, but she doesn't listen ...